During which minute of life should the target saturation first reach 60-65%?

The target saturation of 60-65% is typically expected to be reached during the first minute of life for a newborn. This is an important milestone as it reflects the newborn's transition from fetal to neonatal circulation, where the lungs become functional and oxygenation begins to improve.

In the first minute after birth, the infant's body is adjusting to breathing air, and the establishment of adequate oxygen saturation is crucial for ensuring that the organs receive enough oxygen for normal function. Monitoring this saturation helps healthcare providers assess how well the newborn is adapting and whether any interventions are necessary.

Achieving this target saturation at this early stage indicates that the resuscitation efforts, if any were needed, are effective, and the newborn is successfully starting the process of oxygenating blood through the lungs. Failure to achieve this target could warrant further evaluation and potential resuscitation measures to support the infant's breathing and oxygenation.