What is the proper adjustment for oxygen concentration using an oxygen blender initially?

In the context of neonatal resuscitation, the initial oxygen concentration should carefully consider the infant's condition, particularly if they are term or preterm. Starting with an oxygen concentration of 30% is aligned with current recommendations when initiating resuscitation efforts for newborns.

Research suggests that using a moderate concentration of oxygen (30%) effectively balances the need for oxygen while minimizing the risks associated with excessive oxygen exposure, such as oxidative stress. Newborns, especially those who are preterm, have immature lungs and oxygen saturation levels that need to be carefully monitored and adjusted based on their response to initial resuscitation efforts.

Higher concentrations, such as 50% or 100%, can result in hyperoxia, which may be detrimental by increasing the risk of retinopathy of prematurity and other complications. Meanwhile, a lower starting point, like 20%, may not provide sufficient oxygen to adequately support the infant’s immediate needs during resuscitation. Therefore, beginning with 30% oxygen is the proper approach to ensure effective and safe resuscitation for neonates.